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Computer simulations of the blood flow in right coronary artery with two stenoses in the same arterial segment are carried out to investigate the interactions of serial stenoses, especially the effect of the distal stenosis. Various mathematical models are developed by varying the location of the distal stenosis. The numerical results show that the variation of the distal stenosis has significant impact on coronary hemodynamics, such as the pressure drop, the flow shifting, and the flow separation. Our simulations demonstrate that the distal stenosis has insignificant effect on the disturbed flow pattern in the upstream and across the proximal stenosis regions. In a curved artery segment with two moderate stenoses of the same size, the distal stenosis causes a larger pressure drop and a more disturbed flow field in post stenotic region than the proximal stenosis does. A distal stenosis located at a further downstream position causes a larger pressure drop and a stronger reverse flow.

right coronary artery, serial stenoses, pressure drop, flow disturbance